Laevolac is a synthetic disaccharide derivative of lactulose and acts by its osmotic properties in the luminal fluid. The primary osmotic effect of lactulose, which is not absorbed in the intestine, may be augmented in the distal ileum and colon by bacterial metabolism of the disaccharide to lactate and other organic acids that are only partially absorbed. Another aspect of action of lactulose is reduction of intestinal ammonia, presumably because of reduced production and increased utilization of ammonia by intestinal bacteria and enhanced excretion of ammonia in the faeces. Laevolac is the solution for constipation and hepatic encephalopathy as well. At medium dosage level, light abdominal pain may occur.

DOSAGE AND DIRECTIONS FOR USE:
(A) CONSTIPATION:
Dosages vary widely with the severity of the condition. A relatively large initial dose should be followed by a smaller maintenance dose. Doses are given daily by mouth in a single dose or in 2 divided doses. The full effect may not be attained for a few days.

Recommended dosages are as follows:
USUAL STARTING DOSE:
ADULTS:
30 mL (6 x 5 mL medicine measure)
CHILDREN (6 – 14 years):
CHILDREN (1 – 5 years): 15 mL (3 x 5 mL medicine measure)
INFANTS: 10 mL (2 x 5 mL medicine measure)
MAINTENANCE DOSE: 5 mL (1 x 5 mL medicine measure)

ADULTS:
15 – 30 mL (3 – 6 x 5 mL medicine measure)
10 – 15 mL (2 – 3 x 5 mL medicine measure)
2,5 – 5 mL (½ – 1 x 5 mL medicine measure)
(B) PORTAL SYSTEMIC ENCEPHALOPATHY:
Initial dose of 30 – 50 mL, 3 times daily. Subsequently adjust the dose to produce 2 to 3 soft stools daily.