Arthritis is a common condition that causes pain, inflammation and stiffness in and around one or more of your joints. Osteoarthritis, also known as “wear and tear” arthritis is characterized by progressive degeneration of the cartilage of the joints, occurring mainly in older people. It is also more likely to occur in people who are overweight or obese and in those with jobs that stress particular joints. The condition most frequently affects the joints of knees, hips, hands, lower back and neck.
A typical modern diet that is excessive in omega-6 fatty acids and deficient in omega-3 fatty acids leads to chronic inflammation in your body. Elevated production of arachidonic acid (AA) in the body, as a result of consumption of foods high in omega-6 fatty acids such as red meats, dairy products, eggs and refined oils has shifted the balance of fatty acid metabolism toward an increase in pro-inflammatory metabolite generation, via the LOX (5-lipoxygenase) and COX (cyclooxygenase) enzymatic pathways, causing inflammation, distorted joints and tissue destruction.
NSAIDs are frequently used to inhibit the COX route to relieve the joint pain. However, it induces gastric side effects as COX-1 is responsible for maintenance and protection of the gastrointestinal tract. There are new generation NSAIDs that selectively block only the COX-2 pathway but still allow the production of leukotrienes through the 5-LOX inflammation pathway, which cause devastating effects on joints, arterial walls and other tissues.
OLIFERIN® JOINT FLEX TRIVA contains olive phytonutrients, especially hydroxytyrosol, AKBA (boswellia serrata extract), curcuminoids (turmeric extract) and nutrient enhancer Bioperine® black pepper extract, to offer fast and natural pain relief and support joint and muscular health.
Boswellia Serrata – The Ancient Herb For Joints
Boswellia serrata is a tree producing a highly scented sap that has been prized for its healing properties since ancient times. It preserves healthy muscle & joint mobility, supports normal inflammation processes and helps maintain healthy connective tissues.Of the active compounds in the Boswellia extract, Acetyl-11-keto-ß-boswellic acid (AKBA) has been identified as the most powerful, demonstrating pronounced inhibitory against 5-LOX.
Apresflex® – Fast Acting 5-Lox Inhibitor
ApresFlex® is a clinically tested gum resin extract of boswellia serrata enriched with at least 20% AKBA and its non-volatile oil. Clinical data showed that compared to AKBA alone, the synergism with the non-volatile oil promotes faster absorption, quick and long lasting therapeutic benefits, making it a potent anti-inflammatory agent. Moreover, this novel Boswellia extract significantly inhibits matrix metalloproteinase (MMP-3), enzymes that break down cartilage, collagen and connective tissues.
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