Sulbutiamine has been used to treat asthenia, a condition of low energy and lethargy usually reported by convelescing patients. There is some evidence that it does work and numerous patents regarding this material.

Sulbutiamine is described as a centrally acting cholinergic agent like donepezil which is used for Parkinson’s and Alzheimer symptoms. These drugs inhibit the destruction of acetylcholine (a stimulating neurotransmittor) in the brain. Increased concentrations of acetylcholine are believed to be responsible for greater alertness, memory and acuity.

Sulbutiamine is an ACE inhibitor, which results in greater brain acetylcholine concentrations which would increase concentration, memory, alertness, etc.

Indication:
Symptomatic treatment of all forms of asthenia such as:
•Physical and intellectual overwork
•Difficulty in concentration
•Fatigue not overcome by rest
•Decreased intellectual efficiency and lucidity, especially in the elderly

Directions:
1 – 3 capsules as a single dose or in divided doses.
The average adult dose is take 2 capsules daily with breakfast.